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NOD1 and NOD2 in inflammatory and infectious diseases

17 Jul 2020

Abstract excerpt

It has been long recognized that NOD1 and NOD2 are critical players in the host immune response, primarily by their sensing bacterial peptidoglycan-conserved motifs. Significant advances have been made from efforts that characterize their upstream activators, assembly of signaling complexes, and activation of downstream signaling pathways. Disruption in NOD1 and NOD2 signaling has also been associated with...

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PMID: 32677123
DOI: 10.1111/imr.12902

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