Article
The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis.
Mucosal immunology - 1 Jan 2010
Lavelle E C, Murphy C, O'Neill L A J, Creagh E M
Abstract excerpt
The mucosal surfaces of the gastrointestinal tract are continually exposed to an enormous antigenic load of microbial and dietary origin, yet homeostasis is maintained. Pattern recognition molecules (PRMs) have a key role in maintaining the integrity of the epithelial barrier and in promoting maturation of the mucosal immune system. Commensal bacteria modulate the expression of a broad range of genes involved in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
