Article

Bacterial Peptidoglycan Fragments Differentially Regulate Innate Immune Signaling

2020-09-04

Abstract excerpt

<h4>ABSTRACT</h4> The human innate immune system responds to both pathogen and commensal bacteria at the molecular level using bacterial peptidoglycan (PG) recognition elements. Traditionally, synthetic and commercially accessible PG monosaccharide units known as muramyl dipeptide (MDP) and N -glycolyl MDP (ng-MDP) have been used to probe the mechanism of innate immune activation of pattern recognition receptors...

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Literature Corpus work: f7399d2e-d5ac-5510-95f8-8ca6a76690d7
DOI: 10.1101/2020.09.03.278705

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