Article

A dual role for PGLYRP1 in host defense and immune regulation during <i>B. pertussis</i> infection

2025-09-27

Abstract excerpt

<h4>ABSTRACT</h4> Bordetella pertussis , the etiologic agent of whooping cough, remains a serious public health concern despite widespread vaccination. Improved therapeutics and vaccines are urgently needed to treat and prevent pertussis disease. Host recognition of bacterial peptidoglycan (PGN), including B. pertussis extracellular PGN fragment tracheal cytotoxin (TCT), shapes the immune response to infection....

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Literature Corpus work: 9e4f59b8-3973-5749-a9c1-43eb5b220ece
DOI: 10.1101/2025.09.26.678899

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