Article

A probiotic bi-functional peptidoglycan hydrolase sheds NOD2 ligands to regulate gut homeostasis

2022-09-28

Abstract excerpt

<title>Abstract</title> <p>The secreted protein is one of the direct molecular mechanisms by which microbiota influence the host, thus constituting a promising field for drug discovery. Here, through bioinformatics-guided screening of the secretome of clinically established probiotics from Lactobacillus, an uncharacterized secreted protein (named LPH here) shared by most of these probiotic strains (8/10) was iden...

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Literature Corpus work: 0e4b192b-ef98-5f2c-a5b6-1173525478a4
DOI: 10.21203/rs.3.rs-2043471/v1

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