Back to search

Article

Chromatin regulator <i>Kdm6b</i> is required for the establishment and maintenance of neural stem cells in mouse hippocampus

2024-02-21

Abstract excerpt

<h4>ABSTRACT</h4> Neural stem cells (NSCs) in the mouse hippocampal dentate gyrus (DG) – a structure important to learning and memory – generate new neurons postnatally and throughout adult life. However, the regulators that enable this lifelong neurogenesis remain incompletely understood. Here we show that the chromatin regulator KDM6B is required for both the establishment and maintenance of NSCs in the mouse D...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b3cf5fd0-e820-5005-ad6d-60669574bff5
DOI
10.1101/2024.02.20.581302
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Chromatin regulator <i>Kdm6b</i> is required for the establishment and maintenance of neural stem cells in mouse hippocampusDOI 10.1101/2024.02.20.581302
Epigenetic regulator KDM5B loss-of-function delays neuronal differentiation of human iPSCsSemantic proximity
Blade-dependent molecular identity and neurogenic potential in the adult dentate gyrusSemantic proximity
KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitorsSemantic proximity
The Conserved Transcription Factor Krüppel Regulates the Survival and Neurogenesis of Mushroom Body Neuroblasts in <i>Drosophila</i> Adult BrainsSemantic proximity
A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cellsSemantic proximity
<i>Kdm6a</i> Deficiency Restricted to Mouse Hematopoietic Cells Causes an Age- and Sex-dependent Myelodysplastic Syndrome-Like PhenotypeSemantic proximity
An epigenome atlas of neural progenitors within the embryonic mouse forebrainSemantic proximity
<i>Pgbd5</i> impacts neuronal differentiation and double strand breaks signaling in the developing cortexSemantic proximity
An Integrative Single-Cell Epigenomic Atlas Annotates the Regulatory Genome of the Adult Mouse BrainSemantic proximity
Integrative multi-omics analyses reveal multi-modal FOXG1 functions acting on epigenetic processes and in concert with NEUROD1 to regulate synaptogenesis in the mouse hippocampusSemantic proximity
Spatial Genome Re-organization between Fetal and Adult Hematopoietic Stem CellsSemantic proximity
Pax6 and KDM5C co-occupy a subset of developmentally critical genes including Notch signaling regulators in neural progenitorsSemantic proximity
Select a neighboring publication to make it the new centre.