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The Conserved Transcription Factor Krüppel Regulates the Survival and Neurogenesis of Mushroom Body Neuroblasts in <i>Drosophila</i> Adult Brains

2024-06-26

Abstract excerpt

<h4>Summary</h4> In various metazoans, including Drosophila and humans, neural progenitors exit the cell cycle and are eliminated by the end of development, limiting adult neurogenesis. We demonstrate that in Drosophila, the conserved transcription factor Krüppel ( Kr ) controls neurogenic capacity of a specific subset of neuroblasts that forms the mushroom body (MBNBs), analogous to the mammalian hippocampus...

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Literature Corpus work
60ecd31b-a183-5e10-860f-5bbc93c25d0c
DOI
10.1101/2024.06.25.600704
Open publication

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The Conserved Transcription Factor Krüppel Regulates the Survival and Neurogenesis of Mushroom Body Neuroblasts in <i>Drosophila</i> Adult BrainsDOI 10.1101/2024.06.25.600704
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