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Genetic Correlates of Treatment-Resistant Depression: Insights from Polygenic Scores Across Cognitive, Temperamental, and Sleep Traits in the All of US cohort

2024-07-05

Abstract excerpt

<h4>Background</h4> Treatment-resistant depression (TRD) is a major challenge in mental health, affecting a significant number of patients and leading to considerable economic and social burdens. The etiological factors contributing to TRD are complex and not fully understood. <h4>Objective</h4> To investigate the genetic factors associated with TRD using polygenic scores (PGS) across various traits, and to explor...

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Literature Corpus work
b3915a5a-283e-5696-882e-af5339e7e618
DOI
10.1101/2024.07.03.24309914
Open publication

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Genetic Correlates of Treatment-Resistant Depression: Insights from Polygenic Scores Across Cognitive, Temperamental, and Sleep Traits in the All of US cohortDOI 10.1101/2024.07.03.24309914
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