Article

PhiDsc: Protein functional mutation Identification by 3D Structure Comparison

2022-05-19

Abstract excerpt

Selective pressures that trigger cancer formation and progression shape the mutational landscape of somatic mutations in cancer. Given the limits within which cells are regulated, a growing tumor has access to only a finite number of pathways that it can alter. As a result, tumors arising from different cells of origin often harbor identical genetic alterations. Recent expansive sequencing efforts have identified...

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Literature Corpus work: b385e289-d854-56b0-8747-70273fce57ce
DOI: 10.1101/2022.05.18.492407

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