Article

Identification of CYP2D6 allelic mutations in a sub-set of Karachi population

2021-03-26

Abstract excerpt

CYP2D6 gene polymorphism is considered a main obstacle in the process of drug metabolism under clinical diseases that affect pharmacokinetics of ~25% of antidepressants and other drugs. Inter-individual variation occurs in the amount and functional activity of CYP2D6 enzyme produce undesirable side effects. The primary aim of current research is to evaluate gene and genotypic frequencies of CYP2D6 *1 extensive met...

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Literature Corpus work: b3722103-4acb-5593-a9d3-0caf403bd730
DOI: 10.14293/s2199-1006.1.sor-.ppae8yv.v1

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