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Article

Increased prevalence of functional minor allele variants of drug metabolizing CYP2B6 and CYP2D6 genes in Roma population samples.

Pharmacological reports : PR - 1 Jun 2015

Weber Agnes, Szalai Renata, Sipeky Csilla, Magyari Lili, Melegh Marton, Jaromi Luca, Matyas Petra, Duga Balazs, Kovesdi Erzsebet, Hadzsiev Kinga, Melegh Bela

Abstract excerpt

BACKGROUND: Cytochrome P450 2B6 and 2D6 are important enzymes in human drug metabolism. These phase I enzymes are known to contribute the biotransformation of clinically important pharmaceuticals, including antidepressants, anticancer and anxiolytic drugs. The aim of this work was to determine the pharmacogenetic profile of CYP2B6 and CYP2D6 in Roma and Hungarian population samples. METHODS: A study population of...

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PMID: 25933954
DOI: 10.1016/j.pharep.2014.11.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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