Article

Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder - a retrospective cohort study

2025-10-03

Abstract excerpt

<title>Abstract</title> <p>Cytochrome P450 2D6 (CYP2D6) is a polymorphic enzyme that affects antidepressant metabolism. This retrospective hospital-based cohort study investigated the association between <italic>CYP2D6</italic> genotype and treatment outcomes in 99 hospitalized patients with major depressive disorder (MDD) in Belgrade, Serbia. Patients were classified as poor (PM, n = 5), intermediate (IM, n = 30...

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Literature Corpus work: a083c174-0d8d-5183-bdb4-382164cfee8f
DOI: 10.21203/rs.3.rs-7234296/v1

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