Article

Establishing an RNA sensor with high sensitivity and dynamic range utilizing a signal amplifier platform

2025-09-17

Abstract excerpt

Precise control of gene expression in a cell-state-specific manner is essential for effective therapeutic interventions in complex and dynamic disease microenvironments. Traditional targeting strategies that rely on surface markers or cell type-specific promoters often assume static cellular identities, limiting effectiveness in contexts such as cancer and inflammation, where cell states are highly heterogeneous a...

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Literature Corpus work: b2e8dddd-15c7-5c8b-b31b-b6d5923a17d8
DOI: 10.1101/2025.09.17.675666

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