Article

Programmable RNA Sensing for Cell Monitoring and Manipulation

2022-05-26

Abstract excerpt

<h4>ABSTRACT</h4> RNAs are the central and universal mediator of genetic information underlying the diversity of cell types and cell states, which together shape tissue organization and organismal function across species and life spans. Despite advances in RNA sequencing and massive accumulation of transcriptome datasets across life sciences, the dearth of technologies that leverage RNAs to observe and manipulate...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a802e06a-5b87-53db-b8e5-12252cd59a96
DOI: 10.1101/2022.05.25.493141

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Programmable RNA Sensing for Cell Monitoring and ManipulationDOI 10.1101/2022.05.25.493141Read

Modular and programmable RNA sensing using ADAR editing in living cellsSemantic proximity Read

RNA-programmable cell type monitoring and manipulation in the human cortex with CellREADRSemantic proximity Read

Programmable eukaryotic protein expression with RNA sensorsSemantic proximity Read

Programmable RNA writing with trans-splicingSemantic proximity Read

Leveraging Endogenous ADAR for Programmable Editing on RNASemantic proximity Read

Sensing endogenous RNA in living human cells using a CRISPR-activated proteaseSemantic proximity Read

Targeted RNA editing by direct delivery of an adenosine deaminase-antisense oligo conjugateSemantic proximity Read

Perturbing RNA localization for functional study in neuronsSemantic proximity Read

CRISPR based programmable RNA editing in primary neuronsSemantic proximity Read

Scalable single-cell total RNA-seq reveals non-coding programs in immunity, infection, and brain developmentSemantic proximity Read

Beyond polyA: scalable single-cell total RNA-seq unifies coding and non-coding transcriptomicsSemantic proximity Read

A cytosine deaminase for programmable single-base RNA editingSemantic proximity Read