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Amplification-Free Multi-RNA-Type Profiling for Cancer Risk Stratification via Alternating Current Electrohydrodynamic Nanomixing.

Small (Weinheim an der Bergstrasse, Germany) - 1 Apr 2018

Koo Kevin M, Dey Shuvashis, Trau Matt

Abstract excerpt

Simultaneous analysis of messenger RNA (mRNA), microRNA (miRNA), and long noncoding RNA (lncRNA)-multi-RNA-type profiling-is increasingly crucial in cancer diagnostics. Yet, rapid multi-RNA-type profiling is challenging due to enzymatic amplification reliance and RNA-type-dependent characteristics. Here, a nanodevice is reported to uniquely use alterable alternating current electrohydrodynamic (ac-EHD) forces to...

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PMID: 29527804
DOI: 10.1002/smll.201704025

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