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Article

Design of novel synthetic promoters to tune gene expression in T cells

2025-01-09

Abstract excerpt

<h4>ABSTRACT</h4> Transcriptional control of transgene expression can be linked to dynamic changes in cellular states if this is accompanied by differential expression of transcription factors (TFs). Synthetic promoters (SPs) designed to respond to the desired TFs can provide this regulation with compactness, specificity, and orthogonality. T cells display differentially expressed TFs according to the functional...

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Literature Corpus work
79a295dd-e54d-5908-a648-d4d1add1eefe
DOI
10.1101/2025.01.09.632034
Open publication

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Design of novel synthetic promoters to tune gene expression in T cellsDOI 10.1101/2025.01.09.632034
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