Article

Rapid and Multiplexed Nucleic Acid Detection using Programmable Aptamer-Based RNA Switches

2023-06-06

Abstract excerpt

<h4>ABSTRACT</h4> Rapid, simple, and low-cost diagnostic technologies are crucial tools for combatting infectious disease. Here, we describe a class of aptamer-based RNA switches called aptaswitches that recognize specific target nucleic acid molecules and respond by initiating folding of a reporter aptamer. Aptaswitches can detect virtually any sequence and provide a fast and intense fluorescent readout, generati...

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Literature Corpus work: 71b84494-ee30-5761-af61-8574a6db78d4
DOI: 10.1101/2023.06.02.23290873

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