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Engineered RNA biosensors enable ultrasensitive SARS-CoV-2 detection in a simple color and luminescence assay

2021-01-08

Abstract excerpt

<h4>ABSTRACT</h4> The continued resurgence of the COVID-19 pandemic with multiple variants underlines the need for diagnostic strategies, that are easily adapatable to the changing virus. Here, we have designed and developed toehold RNA-based sensors across the SARS-CoV-2 genome for direct and ultrasensitive detection of the virus and its prominent variants. In our assay, isothermal amplification of a fragment of...

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Literature Corpus work: 1cdf383c-7efc-5842-bbcd-d283e4dd72d4
DOI: 10.1101/2021.01.08.21249426

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