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Early in vivo transcriptomic response of West African Plasmodium falciparum isolates to artemisinin-based combination therapy

2026-06-06

Abstract excerpt

<title>Abstract</title> <p>Artemisinin-based combination therapies (ACTs) remain central to malaria control, yet the mechanisms enabling early parasite survival after treatment in African Plasmodium falciparum populations are poorly understood. We combined in vivo parasite genotyping and transcriptomic profiling to investigate early responses to ACT in clinically sensitive West African isolates collected before t...

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Literature Corpus work
b2dab2c9-5ad6-55fb-82b0-8e3840aa7296
DOI
10.21203/rs.3.rs-9639294/v1
Open publication

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Early in vivo transcriptomic response of West African Plasmodium falciparum isolates to artemisinin-based combination therapyDOI 10.21203/rs.3.rs-9639294/v1
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