Article

Population genomics and transcriptomics of Plasmodium falciparum uncover components of the artemisinin resistance genetic background.

2023-10-20

Abstract excerpt

<title>Abstract</title> <p>The emergence and spread of <italic>Plasmodium falciparum</italic> lineages resistant to artemisinins is threatening the efficacy of Artemisinin Combination Therapies (ACTs), the global first-line treatment for <italic>falciparum</italic> malaria. Artemisinin resistance is a complex genetic trait in which nonsynonymous SNPs in <italic>PfK13</italic> cooperate with other, currently unkno...

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Literature Corpus work: 56077592-1582-522f-b6af-430f6679ae17
DOI: 10.21203/rs.3.rs-3404050/v1

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