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Article

Persistence of Plasmodium falciparum parasitemia after artemisinin combination therapy: evidence from a randomized trial in Uganda.

Scientific reports - 20 May 2016

Chang Hsiao-Han, Meibalan Elamaran, Zelin Justin, Daniels Rachel, Eziefula Alice C, Meyer Evan C, Tadesse Fitsum, Grignard Lynn, Joice Regina C, Drakeley Chris, Wirth Dyann F, Volkman Sarah K, Buckee Caroline, Bousema Teun, Marti Matthias

Abstract excerpt

Artemisinin resistance is rapidly spreading in Southeast Asia. The efficacy of artemisinin-combination therapy (ACT) continues to be excellent across Africa. We performed parasite transcriptional profiling and genotyping on samples from an antimalarial treatment trial in Uganda. We used qRT-PCR and genotyping to characterize residual circulating parasite populations after treatment with either ACT or...

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Identifiers

PMID: 27197604
DOI: 10.1038/srep26330
PMCID: PMC4873826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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