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Dihydroartemisinin induces a two-step transcriptional response and stage-specific developmental shifts in malaria parasites, <i>Plasmodium falciparum</i>

2026-06-18

Abstract excerpt

The parasite Plasmodium falciparum causes malaria, the deadliest human parasitic disease, which remains fatal when not promptly treated. Evolving parasite resistance to frontline artemisinin-based therapies threatens vulnerable populations and decades of progress toward malaria elimination. Yet the mode of action of dihydroartemisinin (DHA), the active metabolite of these treatments, remains incompletely understo...

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Literature Corpus work
1f2f9af7-142a-5a2e-93b7-cb91f015d6a9
DOI
10.64898/2026.06.16.732544
Open publication

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Dihydroartemisinin induces a two-step transcriptional response and stage-specific developmental shifts in malaria parasites, <i>Plasmodium falciparum</i>DOI 10.64898/2026.06.16.732544
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