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Single-cell RNA profiling of <i>Plasmodium vivax</i> -infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets

2022-02-01

Abstract excerpt

<h4>ABSTRACT</h4> The resilience of Plasmodium vivax , the most widely distributed malaria-causing parasite in humans, is attributed to its ability to produce dormant liver forms known as hypnozoites, which can activate weeks, months, or even years after an initial mosquito bite. The factors underlying hypnozoite formation and activation are poorly understood, as is the parasite’s influence on the host hepatocyt...

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Literature Corpus work
a76dcbe8-8a38-5fbf-a46c-2d10c430e9c8
DOI
10.1101/2022.02.01.478648
Open publication

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Single-cell RNA profiling of <i>Plasmodium vivax</i> -infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targetsDOI 10.1101/2022.02.01.478648
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