Article

Immunosuppression in the prostate tumor microenvironment is tied to androgen deprivation therapy-resistant club-like cells

2024-03-28

Abstract excerpt

Prostate cancer treatment resistance is a significant challenge facing the field. Genomic and transcriptomic profiling have partially elucidated the mechanisms through which cancer cells escape treatment, but their relation toward the tumor microenvironment (TME) remains elusive. Here we present a comprehensive transcriptomic landscape of the prostate TME at multiple points in the standard treatment timeline emplo...

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Literature Corpus work: b2ce1e34-2013-5a4e-b56c-d729a61f32c3
DOI: 10.1101/2024.03.25.586330

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