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Article

Resolving the immune landscape of human prostate at a single-cell level in health and cancer

1 Dec 2021

Abstract excerpt

The prostate gland produces prostatic fluid, high in zinc and citrate and essential for the maintenance of spermatozoa. Prostate cancer is a common condition with limited treatment efficacy in castration-resistant metastatic disease, including with immune checkpoint inhibitors. Using single-cell RNA-sequencing to perform an unbiased assessment of the cellular landscape of human prostate, we identify a subset of...

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PMID: 34936871
DOI: 10.1016/j.celrep.2021.110132

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