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Occurrences and Functions of Ly6Chi and Ly6Clo Macrophages in Health and Disease

30 May 2022

Abstract excerpt

Macrophages originating from the yolk sac or bone marrow play essential roles in tissue homeostasis and disease. Bone marrow-derived monocytes differentiate into Ly6C hi and Ly6C lo macrophages according to the differential expression of the surface marker protein Ly6C. Ly6C hi and Ly6C lo cells possess diverse functions and transcriptional profiles and can accelerate the disease process or support tissue repair...

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PMID: 35707538
DOI: 10.3389/fimmu.2022.901672

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