Article
Transcriptomic Analysis of Monocyte-Derived Non-Phagocytic Macrophages Favors a Role in Limiting Tissue Repair and Fibrosis.
Frontiers in immunology - 1 Jan 2020
Butenko Sergei, Satyanarayanan Senthil K, Assi Simaan, Schif-Zuck Sagie, Sher Noa, Ariel Amiram
Abstract excerpt
Monocyte-derived macrophages are readily differentiating cells that adapt their gene expression profile to environmental cues and functional needs. During the resolution of inflammation, monocytes initially differentiate to reparative phagocytic macrophages and later to pro-resolving non-phagocytic macrophages that produce high levels of IFNβ to boost resolutive events. Here, we performed in-depth analysis of...
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