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Article

INSM1 Regulates Neuroendocrine Plasticity and Tumor Progression in Prostate Cancer

2026-07-31

Abstract excerpt

<h4> Abstract </h4> Neuroendocrine prostate cancer (NEPC) is a highly aggressive and therapy-resistant subtype that arises from adenocarcinoma through lineage plasticity; however, the molecular mechanisms driving this transition remain incompletely defined. Insulinoma-associated protein 1 (INSM1), a zinc-finger transcription factor and established neuroendocrine lineage marker, has been implicated in a variety o...

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Literature Corpus work
b1c61686-9bcc-5ba0-92da-13e2422708f8
DOI
10.64898/2026.07.30.741780
Open publication

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INSM1 Regulates Neuroendocrine Plasticity and Tumor Progression in Prostate CancerDOI 10.64898/2026.07.30.741780
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