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Article

A novel role for Neurog2 in MYCN driven neuroendocrine plasticity of prostate cancer

2024-08-19

Abstract excerpt

<h4>Summary</h4> Neuroendocrine prostate cancer (NEPC) presents a formidable clinical challenge owing to its aggressive progression and resistance to conventional therapies. A key driver of NEPC is the overexpression of MYCN , a well-established oncogene associated with neuroendocrine tumors. However, efforts to directly inhibit the N-Myc protein encoded by this gene have resulted in limited success, thereby hin...

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Identifiers and source

Literature Corpus work
f89459d9-fe9e-5ee6-9069-c2222830ff77
DOI
10.1101/2024.08.16.607954
Open publication

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A novel role for Neurog2 in MYCN driven neuroendocrine plasticity of prostate cancerDOI 10.1101/2024.08.16.607954
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