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Article

Role of MicroRNAs in Neuroendocrine Prostate Cancer

30 Mar 2022

Abstract excerpt

Therapy-induced neuroendocrine prostate cancer (t-NEPC/NEPC) is an aggressive variant of prostate cancer (PCa) that frequently emerges in castration-resistant prostate cancer (CRPC) under the selective pressure of androgen receptor (AR)-targeted therapies. This variant is extremely aggressive, metastasizes to visceral organs, tissues, and bones despite low serum PSA, and is associated with poor survival rates. It...

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PMID: 35447888
DOI: 10.3390/ncrna8020025

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