Article

The genomic landscape of early stage ovarian high grade serous carcinoma

2021-05-05

Abstract excerpt

<h4>Purpose</h4> High grade serous carcinoma (HGSC) is the commonest type of ovarian cancer. Nearly all HGSC cases are diagnosed at late stage and it is not clear whether early stage HGSC has unique characteristics compared to late stage tumours. <h4>Experimental Design</h4> We analysed samples from 45 patients with FIGO stage I - IIA HGSC - 40 from the pathology archives of three large UK cancer centres and 5 f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b16e31b2-2065-5c6b-b13a-52889bfb5e58
DOI: 10.1101/2021.05.05.440631

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The genomic landscape of early stage ovarian high grade serous carcinomaDOI 10.1101/2021.05.05.440631Read

The Genomic Landscape of Early-Stage Ovarian High-Grade Serous Carcinoma.Semantic proximity Read

The genomic trajectory of ovarian high grade serous carcinoma is determined in STIC lesionsSemantic proximity Read

The Changing View of High-Grade Serous Ovarian CancerSemantic proximity Read

Whole exome sequencing of low grade serous ovarian carcinoma identifies genomic events associated with clinical outcome.Semantic proximity Read

Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivorsSemantic proximity Read

TP53 mutations, tetraploidy and homologous recombination repair defects in early stage high-grade serous ovarian cancer.Semantic proximity Read

Integrated genomic and histopathological analysis of low grade serous ovarian carcinoma identifies clinically distinct disease subtypesSemantic proximity Read

Multiomic characterisation of high grade serous ovarian carcinoma enables high resolution patient stratificationSemantic proximity Read

Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survivalSemantic proximity Read

The genomic landscape of recurrent ovarian high grade serous carcinoma: the BriTROC-1 studySemantic proximity Read

Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors.Semantic proximity Read

Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes.Semantic proximity Read