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The Changing View of High-Grade Serous Ovarian Cancer

17 May 2012

Abstract excerpt

The classification of epithelial ovarian cancer has been substantially revised, with an increased appreciation of the cellular origins and molecular aberrations of the different histotypes. Distinct patterns of signaling-pathway disruption are seen between and within histotypes. Large-scale genomic studies of high-grade serous cancer, the most common histotype, have identified novel molecular subtypes that are...

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PMID: 22593197
DOI: 10.1158/0008-5472.can-11-3911

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