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Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long- and short-term survivors

31 Oct 2018

Abstract excerpt

BACKGROUND: Patients diagnosed with high-grade serous ovarian cancer (HGSOC) who received initial debulking surgery followed by platinum-based chemotherapy can experience highly variable clinical responses. A small percentage of women experience exceptional long-term survival (long term (LT), 10+ years), while others develop primary resistance to therapy and succumb to disease in less than 2 years (short term...

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PMID: 30382883
DOI: 10.1186/s13073-018-0590-x

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