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Integrated genomic and histopathological analysis of low grade serous ovarian carcinoma identifies clinically distinct disease subtypes

2022-02-02

Abstract excerpt

<h4>Background</h4> Low-grade serous ovarian carcinoma (LGSOC) is a distinct, under-investigated and relatively chemotherapy-resistant ovarian cancer type. Understanding the molecular landscape is crucial to maximise the impact of molecularly-targeted therapy. <h4>Methods</h4> Whole exome sequencing and copy number data were integrated with histopathological patterns, ER/PR expression, and detailed clinical annota...

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Literature Corpus work
a6b12bac-c22b-57d0-b11a-687a1f52dd11
DOI
10.1101/2022.02.01.22270258
Open publication

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Integrated genomic and histopathological analysis of low grade serous ovarian carcinoma identifies clinically distinct disease subtypesDOI 10.1101/2022.02.01.22270258
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