Article

The genomic landscape of recurrent ovarian high grade serous carcinoma: the BriTROC-1 study

2022-10-25

Abstract excerpt

The drivers of recurrence and resistance in ovarian high grade serous carcinoma (HGSC) remain unclear. We established BriTROC-1 to investigate the acquisition of resistance by collecting tumour biopsies from women with recurrent ovarian HGSC that had relapsed following at least one line of platinum-based chemotherapy. Patients underwent biopsy or secondary debulking surgery, with tumour samples fixed in methanol-b...

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Literature Corpus work: 132b2f14-9579-5e35-a01d-32edad100bc1
DOI: 10.1101/2022.10.21.22280992

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