Article
Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors.
Journal of translational medicine - 17 Dec 2022
Wong Kwong-Kwok, Bateman Nicholas W, Ng Chun Wai, Tsang Yvonne T M, Sun Charlotte S, Celestino Joseph, Nguyen Tri V, Malpica Anais, Hillman R Tyler, Zhang Jianhua, Futreal P Andrew, Rojas Christine, Conrads Kelly A, Hood Brian L, Dalgard Clifton L, Wilkerson Matthew D, Phippen Neil T, Conrads Thomas P, Maxwell George L, Sood Anil K, Gershenson David M
Abstract excerpt
BACKGROUND: Low-grade serous ovarian cancer (LGSOC) is a rare disease that occurs more frequently in younger women than those with high-grade disease. The current treatment is suboptimal and a better understanding of the molecular pathogenesis of this disease is required. In this study, we compared the proteogenomic analyses of LGSOCs from short- and long-term survivors (defined as < 40 and > 60 months,...
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