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Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival

3 Jul 2023

Abstract excerpt

High-grade serous ovarian cancer (HGSC) is the most lethal histotype of ovarian cancer and the majority of cases present with metastasis and late-stage disease. Over the last few decades, the overall survival for patients has not significantly improved, and there are limited targeted treatment options. We aimed to better characterize the distinctions between primary and metastatic tumors based on short- or...

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PMID: 37400526
DOI: 10.1038/s42003-023-05026-3

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