Article

Anesthetic-Binding Induced Motion of GABA <sub>A</sub> Receptors Revealed by Coarse-Grained Molecular Dynamics Simulations

2023-03-12

Abstract excerpt

General anesthetics are indispensable in modern medicine because they induce a reversible loss of consciousness and sensation in humans. On the other hand, their molecular mechanisms of action have not yet been elucidated. Several studies have identified the main targets of some general anesthetics. The structures of γ-aminobutyric acid A (GABA A ) receptors with the intravenous anesthetics such as propofol and e...

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Literature Corpus work: b1453e38-6c2e-5804-af8d-093e22b2a246
DOI: 10.1101/2023.03.10.530555

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