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Article

Homology model of the GABAA receptor examined using Brownian dynamics.

Biophysical journal - 1 May 2005

O'Mara Megan, Cromer Brett, Parker Michael, Chung Shin-Ho

Abstract excerpt

We have developed a homology model of the GABA(A) receptor, using the subunit combination of alpha1beta2gamma2, the most prevalent type in the mammalian brain. The model is produced in two parts: the membrane-embedded channel domain and the extracellular N-terminal domain. The pentameric transmembrane domain model is built by modeling each subunit by homology with the equivalent subunit of the heteropentameric...

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Identifiers

PMID: 15749776
DOI: 10.1529/biophysj.104.051664
PMCID: PMC1305477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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