Article

Cas9-Assisted Targeting of CHromosome segments (CATCH) for targeted nanopore sequencing and optical genome mapping

2017-02-20

Abstract excerpt

<h4>ABSTRACT</h4> Variations in the genetic code, from single point mutations to large structural or copy number alterations, influence susceptibility, onset, and progression of genetic diseases and tumor transformation. Next-generation sequencing analysis is unable to reliably capture aberrations larger than the typical sequencing read length of several hundred bases. Long-read, single-molecule sequencing method...

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Literature Corpus work: b106a2e9-523b-5ab8-ba7a-d76090023b64
DOI: 10.1101/110163

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