Article

Botulinum neurotoxins are zinc proteins.

1992-11-01

Abstract excerpt

The available amino acid sequences of 150-kDa botulinum and tetanus neurotoxins show the presence of a closely homologous segment in the middle of the light chain (NH2-terminal 50 kDa), which is the intracellularly active portion of the toxin. This segment contains the zinc binding motif of metalloendopeptidases, HEXXH. Atomic adsorption analysis of botulinum neurotoxins (serotypes A, B, and E) made on the basis o...

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Identifiers and source

Literature Corpus work: b101af7e-e29f-510c-9bcc-6d8bc413db17
DOI: 10.1016/s0021-9258(18)35863-0

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