Challenges in searching for therapeutics against Botulinum Neurotoxins

Abstract excerpt

INTRODUCTION: Botulinum neurotoxins (BoNTs) are the most potent toxins known. BoNTs are responsible for botulism, a deadly neuroparalytic syndrome caused by the inactivation of neurotransmitter release at peripheral nerve terminals. Thanks to their specificity and potency, BoNTs are both considered potential bio-weapons and therapeutics of choice for a variety of medical syndromes. Several variants of BoNTs have...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Botulinum Toxin and Related Neurological Disorders
• Share to Hereditary Neurological Disorders
• Share to Neurological disorders and treatments