Article

COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types

2020-12-02

Abstract excerpt

<h4>ABSTRACT</h4> Common genetic polymorphisms associated with severity of COVID-19 illness can be utilized for discovering molecular pathways and cell types driving disease pathogenesis. Here, we assessed the effects of 679 COVID-19-risk variants on gene expression in a wide-range of immune cell types. Severe COVID-19-risk variants were significantly associated with the expression of 11 protein-coding genes, and...

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Literature Corpus work: b0d490ee-db29-5f74-b5a7-9904f4fd41b0
DOI: 10.1101/2020.12.01.407429

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