Article

Human genetic variants associated with COVID-19 severity are enriched in immune and epithelium regulatory networks

2021-12-21

Abstract excerpt

Human genetic variants can influence the severity of infection with SARS-COV-2. Several genome-wide association studies (GWAS) have been conducted to identify human risk loci that may be involved with COVID-19 severity. However, candidate genes were investigated in the genomic proximity of each locus without considering their functional cellular contexts. Here, we compiled regulatory networks of 77 human contexts...

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Literature Corpus work: 29608a82-0b27-5a2b-9a9f-c0b77a8a27dd
DOI: 10.1101/2021.12.17.473140

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