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Single cell sequencing analysis uncovers genetics-influenced CD16+monocytes and memory CD8+T cells involved in severe COVID-19

2022-02-07

Abstract excerpt

<h4>Background</h4> Understanding the host genetic architecture and viral immunity contributes to the development of effective vaccines and therapeutics for controlling the COVID-19 pandemic. Alterations of immune responses in peripheral blood mononuclear cells play a crucial role in the detrimental progression of COVID-19. However, the effects of host genetic factors on immune responses for severe COVID-19 remain...

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Literature Corpus work
570e2cbf-7ed3-5c5c-9b6f-ac1f51c6d73f
DOI
10.1101/2022.02.06.21266924
Open publication

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Single cell sequencing analysis uncovers genetics-influenced CD16+monocytes and memory CD8+T cells involved in severe COVID-19DOI 10.1101/2022.02.06.21266924
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