Article

A simple approximation to bias in gene-environment interaction estimates when a case might not be the case

2018-10-16

Abstract excerpt

<h4>ABSTRACT</h4> Case-control genetic association studies are often used to examine the role of the genetic basis in complex diseases, such as cancer and neurodegenerative diseases. The role of the genetic basis might vary by non-genetic (environmental) measures, what is traditionally defined as gene-environment interactions (GxE). A commonly overlooked complication is that the set of clinically diagnosed cases...

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Literature Corpus work: b0b28798-f2bf-5d2e-b8bb-d80200787ac6
DOI: 10.1101/444588

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