Article

Interactions and collider bias in case-only gene-environment data

2017-04-10

Abstract excerpt

<h4>Background: </h4> Case-only design for gene-environment interaction (CODGEI) relies on the rare disease assumption. A negative association due to collider bias appears between gene and environment when this assumption is not respected. Genetic risk estimation can quantify part of the predisposition of an individual to a disease. <h4>Methods:</h4> We introduce Disease As Collider (DAC), a new case-only methodol...

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Literature Corpus work: 4fc54a6f-d608-5fac-982f-e14bd1990c6b
DOI: 10.1101/124560

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