Joint effect of genes and environment distorted by selection biases: implications for hospital-based case-control studies.

Abstract excerpt

The hospital-based case-control design enhances the response rates in studies that require the collection of biological samples from all of the participants. There are simple, established criteria for selecting controls so as to estimate the effect of a single factor without bias, but the analogous requirements for assessing an interaction are less clear. We derive these conditions by calculating the potential...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Case-Control Studies
• Share to Confounding Factors, Epidemiologic