Article
Estimating the contribution of genetic variants to difference in incidence of disease between population groups.
European journal of human genetics : EJHG - 1 Aug 2012
Moonesinghe Ramal, Ioannidis John P A, Flanders W Dana, Yang Quanhe, Truman Benedict I, Khoury Muin J
Abstract excerpt
Genome-wide association studies have identified multiple genetic susceptibility variants to several complex human diseases. However, risk-genotype frequency at loci showing robust associations might differ substantially among different populations. In this paper, we present methods to assess the contribution of genetic variants to the difference in the incidence of disease between different population groups for...
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