Article

A Simple Approximation To The Bias Of Gene-Envinornment Interactions In Case/Control Studies With Silent Disease

2018-10-17

Abstract excerpt

One of the most important research areas in case-control Genome-Wide Association Studies is to determine how the effect of a genotype varies across the environment or to measure the gene-environment interaction (GxE). We consider the scenario when some of the “healthy” controls actually have the disease and when the frequency of these latent cases varies by the environmental variable of interest. In this scenario,...

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Literature Corpus work: 8c2174aa-bbde-5fa3-9769-13e7a775ff66
DOI: 10.1101/444596

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